Desmond A Schatz

Desmond A Schatz, M.D.

Interim Chair And Professor

Department: MD-PEDS-ADMINISTRATION
Business Phone: (352) 273-9270
Business Email: schatz@ufl.edu

About Desmond A Schatz

Dr. Schatz is Interim Chair, UF College of Medicine Department of Pediatrics; Interim Physician-in-chief, UF Health Shands Children’s Hospital; Medical Director of the Diabetes Center and Associate Director of the GCRC at the University of Florida, Gainesville. He is a physician-scientist and is the Principal Investigator (PI) on multiple funded peer reviewed grants from the National Institutes of Health (NIH) and the Juvenile Diabetes Research Foundation (JDRF). He is currently PI of the University of Florida Clinical Center participating in the NIH-funded international network (TrialNet) aimed at preventing Type 1 diabetes. He is also PI on JDRF funded studies aimed at reversing Type1 diabetes using autologous stem cells (cord blood) and serves as co-PI on a Program Project Grant examining the immunopathogenesis of Type 1 diabetes. He is co-PI for NIH-funded newborn genetic screening (PANDA) studies in North Central Florida as well as the international TEDDY consortium aimed at identifying triggers of the disease. He has served in numerous capacities for the American Diabetes Association, on the Lawson Wilkins Pediatric Endocrine Society and on study review panels for the NIH and JDRF. He also serves on the external advisory board for the NIH- and CDC-funded SEARCH study and the TODAY study in youth with type 2 diabetes and on the JDRF-funded Australian INIT II studies.

Accomplishments

Faculty Member Nominee
2013 · Alpha Omega Alpha (AOA) National Medical Society
Public Policy Leadership Award
2010 · American Diabetes Association
Cure Award
2009 · American Diabetes Association
Clinical Research
2008 · Juvenile Diabetes Foundation

Board Certifications

  • Pediatric Endocrinology
    American Board of Pediatrics
  • Pediatrics
    American Board of Pediatrics

Clinical Profile

Specialties
  • Pediatrics
Subspecialties
  • Pediatric Endocrinology
Areas of Interest
  • Diabetes
  • High blood pressure – adults
  • Obesity in children
  • Type 1 diabetes

Research Profile

Areas of Interest
  • Child Obesity
  • Pediatric Endocrinology
  • Type 1 Diabetes

Publications

2021
A comparison of two hybrid closed-loop systems in adolescents and young adults with type 1 diabetes (FLAIR): a multicentre, randomised, crossover trial.
Lancet (London, England). 397(10270):208-219 [DOI] 10.1016/S0140-6736(20)32514-9. [PMID] 33453783.
2021
A unified mathematical model of thyroid hormone regulation and implication for personalized treatment of thyroid disorders.
Journal of theoretical biology. 528 [DOI] 10.1016/j.jtbi.2021.110853. [PMID] 34358537.
2021
Altered cellular localisation and expression, together with unconventional protein trafficking, of prion protein, PrPC, in type 1 diabetes.
Diabetologia. 64(10):2279-2291 [DOI] 10.1007/s00125-021-05501-8. [PMID] 34274990.
2021
An Age-Related Exponential Decline in the Risk of Multiple Islet Autoantibody Seroconversion During Childhood.
Diabetes care. [DOI] 10.2337/dc20-2122. [PMID] 33627366.
2021
Cost-Effectiveness of Low-Dose Antithymocyte Globulin Versus Other Immunotherapies for Treatment of New-Onset Type 1 Diabetes.
Diabetes technology & therapeutics. [DOI] 10.1089/dia.2021.0329. [PMID] 34704801.
2021
Defining a cure for type 1 diabetes: a call to action.
The lancet. Diabetes & endocrinology. 9(9):553-555 [DOI] 10.1016/S2213-8587(21)00181-9. [PMID] 34339632.
2021
Delayed diagnosis of diabetic ketoacidosis and associated mortality during the COVID-19 pandemic.
Journal of diabetes. 13(10):837-839 [DOI] 10.1111/1753-0407.13208. [PMID] 34196115.
2021
Exocrine Pancreatic Enzymes Are a Serological Biomarker for Type 1 Diabetes Staging and Pancreas Size.
Diabetes. 70(4):944-954 [DOI] 10.2337/db20-0995. [PMID] 33441381.
2021
Genetic Composition and Autoantibody Titers Model the Probability of Detecting C-Peptide Following Type 1 Diabetes Diagnosis.
Diabetes. 70(4):932-943 [DOI] 10.2337/db20-0937. [PMID] 33419759.
2021
How Do We Move Type 1 Diabetes Immunotherapies Forward During the Current COVID-19 Pandemic?
Diabetes. 70(5):1021-1028 [DOI] 10.2337/dbi20-0045. [PMID] 33632743.
2021
IL-6 receptor blockade does not slow β cell loss in new-onset type 1 diabetes.
JCI insight. 6(21) [DOI] 10.1172/jci.insight.150074. [PMID] 34747368.
2021
Image-Based Machine Learning Algorithms for Disease Characterization in the Human Type 1 Diabetes Pancreas.
The American journal of pathology. 191(3):454-462 [DOI] 10.1016/j.ajpath.2020.11.010. [PMID] 33307036.
2021
Immune Intervention in Type 1 Diabetes.
Diabetes technology & therapeutics. 23(S2):S179-S184 [DOI] 10.1089/dia.2021.2513. [PMID] 34061634.
2021
Index60 as an additional diagnostic criterion for type 1 diabetes.
Diabetologia. 64(4):836-844 [DOI] 10.1007/s00125-020-05365-4. [PMID] 33496819.
2021
Insulin immunotherapy for pretype 1 diabetes.
Current opinion in endocrinology, diabetes, and obesity. 28(4):390-396 [DOI] 10.1097/MED.0000000000000648. [PMID] 34091488.
2021
Integrative analyses of TEDDY Omics data reveal lipid metabolism abnormalities, increased intracellular ROS and heightened inflammation prior to autoimmunity for type 1 diabetes.
Genome biology. 22(1) [DOI] 10.1186/s13059-021-02262-w. [PMID] 33478573.
2021
Islet sympathetic innervation and islet neuropathology in patients with type 1 diabetes.
Scientific reports. 11(1) [DOI] 10.1038/s41598-021-85659-8. [PMID] 33753784.
2021
Lived Experience of Advanced Hybrid Closed-Loop Versus Hybrid Closed-Loop: Patient-Reported Outcomes and Perspectives.
Diabetes technology & therapeutics. [DOI] 10.1089/dia.2021.0153. [PMID] 34270328.
2021
Low-Dose ATG/GCSF in Established Type 1 Diabetes: A Five-Year Follow-up Report.
Diabetes. 70(5):1123-1129 [DOI] 10.2337/db20-1103. [PMID] 33632742.
2021
Monogenic Diabetes and Integrated Stress Response Genes Display Altered Gene Expression in Type 1 Diabetes.
Diabetes. 70(8):1885-1897 [DOI] 10.2337/db21-0070. [PMID] 34035041.
2021
The influence of selection bias on identifying an association between allergy medication use and SARS-CoV-2 infection.
EClinicalMedicine. 37 [DOI] 10.1016/j.eclinm.2021.100936. [PMID] 34104879.
2020
Addressing health disparities in type 1 diabetes through peer mentorship.
Pediatric diabetes. 21(1):120-127 [DOI] 10.1111/pedi.12935. [PMID] 31617648.
2020
An Iterative Process for Identifying Pediatric Patients With Type 1 Diabetes: Retrospective Observational Study.
JMIR medical informatics. 8(9) [DOI] 10.2196/18874. [PMID] 32886067.
2020
Comparing Beta Cell Preservation Across Clinical Trials in Recent-Onset Type 1 Diabetes.
Diabetes technology & therapeutics. 22(12):948-953 [DOI] 10.1089/dia.2020.0305. [PMID] 32833543.
2020
Exocrine Pancreas Dysfunction in Type 1 Diabetes.
Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists. 26(12):1505-1513 [DOI] 10.4158/EP-2020-0295. [PMID] 33471743.
2020
Hierarchical Order of Distinct Autoantibody Spreading and Progression to Type 1 Diabetes in the TEDDY Study.
Diabetes care. 43(9):2066-2073 [DOI] 10.2337/dc19-2547. [PMID] 32641373.
2020
Histological validation of a type 1 diabetes clinical diagnostic model for classification of diabetes.
Diabetic medicine : a journal of the British Diabetic Association. 37(12):2160-2168 [DOI] 10.1111/dme.14361. [PMID] 32634859.
2020
Immune Intervention in Type 1 Diabetes.
Diabetes technology & therapeutics. 22(S1):S141-S148 [DOI] 10.1089/dia.2020.2511. [PMID] 32069151.
2020
Insulin dose optimization using an automated artificial intelligence-based decision support system in youths with type 1 diabetes.
Nature medicine. 26(9):1380-1384 [DOI] 10.1038/s41591-020-1045-7. [PMID] 32908282.
2020
Insulin-Like Growth Factor Dysregulation Both Preceding and Following Type 1 Diabetes Diagnosis.
Diabetes. 69(3):413-423 [DOI] 10.2337/db19-0942. [PMID] 31826866.
2020
Introducing the Endotype Concept to Address the Challenge of Disease Heterogeneity in Type 1 Diabetes.
Diabetes care. 43(1):5-12 [DOI] 10.2337/dc19-0880. [PMID] 31753960.
2020
Multiplexing DNA methylation markers to detect circulating cell-free DNA derived from human pancreatic beta-cells
JCI Insight. 5(14) [DOI] 10.1172/jci.insight.136579. [PMID] 32573495.
2020
Slowed Metabolic Decline After 1 Year of Oral Insulin Treatment Among Individuals at High Risk for Type 1 Diabetes in the Diabetes Prevention Trial-Type 1 (DPT-1) and TrialNet Oral Insulin Prevention Trials.
Diabetes. 69(8):1827-1832 [DOI] 10.2337/db20-0166. [PMID] 32439823.
2020
Teaching Type 1 Diabetes: Creating Stakeholder Engagement in Biomedical Careers Through Undergraduate Research Curriculum.
Medical science educator. 30(1):69-73 [DOI] 10.1007/s40670-019-00877-0. [PMID] 34457640.
2020
Temporal Analysis of Amylase Expression in Control, Autoantibody-Positive, and Type 1 Diabetes Pancreatic Tissues.
Diabetes. 69(1):60-66 [DOI] 10.2337/db19-0554. [PMID] 31597639.
2020
The Discovery and Structure of Human Insulin.
Pediatric endocrinology reviews : PER. 17(Suppl 1):131-137 [DOI] 10.17458/per.vol17.2020.zfs.discoverystructureinsulin. [PMID] 32208558.
2020
Use of Ecological Momentary Assessment to Measure Self-Monitoring of Blood Glucose Adherence in Youth With Type 1 Diabetes.
Diabetes spectrum : a publication of the American Diabetes Association. 33(3):280-289 [DOI] 10.2337/ds19-0041. [PMID] 32848350.
2019
An Anti-CD3 Antibody, Teplizumab, in Relatives at Risk for Type 1 Diabetes.
The New England journal of medicine. 381(7):603-613 [DOI] 10.1056/NEJMoa1902226. [PMID] 31180194.
2019
Association of Gluten Intake During the First 5 Years of Life With Incidence of Celiac Disease Autoimmunity and Celiac Disease Among Children at Increased Risk
Jama-Journal of the American Medical Association. 322(6):514-523 [DOI] 10.1001/jama.2019.10329. [PMID] 31408136.
2019
Bringing closure: towards achieving a better understanding of Israel.
Lancet (London, England). 394(10198) [DOI] 10.1016/S0140-6736(19)31760-X. [PMID] 31376991.
2019
Clinical Targets for Continuous Glucose Monitoring Data Interpretation: Recommendations From the International Consensus on Time in Range.
Diabetes care. 42(8):1593-1603 [DOI] 10.2337/dci19-0028. [PMID] 31177185.
2019
Designing Online and Mobile Diabetes Education for Fathers of Children With Type 1 Diabetes: Mixed Methods Study.
JMIR diabetes. 4(3) [DOI] 10.2196/13724. [PMID] 31389338.
2019
Early Probiotic Supplementation and the Risk of Celiac Disease in Children at Genetic Risk
Nutrients. 11(8) [DOI] 10.3390/nu11081790. [PMID] 31382440.
2019
Enhanced Understanding of the Natural History of Pre-Type 1 Diabetes: Fundamental to Prevention.
Pediatric endocrinology reviews : PER. 16(3):359-368 [DOI] 10.17458/per.vol16.2019.bs.pretype1diabetes. [PMID] 30888126.
2019
Genetic risk for autoimmunity is associated with distinct changes in the human gut microbiome.
Nature communications. 10(1) [DOI] 10.1038/s41467-019-11460-x. [PMID] 31399563.
2019
Immune Intervention in Type 1 Diabetes.
Diabetes technology & therapeutics. 21(S1):S95-S100 [DOI] 10.1089/dia.2019.2507. [PMID] 30785317.
2019
Immunomodulatory activity of humanized anti-IL-7R monoclonal antibody RN168 in subjects with type 1 diabetes.
JCI insight. 4(24) [DOI] 10.1172/jci.insight.126054. [PMID] 31852846.
2019
International Consensus on Risk Management of Diabetic Ketoacidosis in Patients With Type 1 Diabetes Treated With Sodium-Glucose Cotransporter (SGLT) Inhibitors.
Diabetes care. 42(6):1147-1154 [DOI] 10.2337/dc18-2316. [PMID] 30728224.
2019
Is It Time to Prioritize Diabetes Prevention in Practice?
Journal of the American Board of Family Medicine : JABFM. 32(4):457-459 [DOI] 10.3122/jabfm.2019.04.190114. [PMID] 31343975.
2019
Low-Dose Anti-Thymocyte Globulin Preserves C-Peptide, Reduces HbA1c, and Increases Regulatory to Conventional T-Cell Ratios in New-Onset Type 1 Diabetes: Two-Year Clinical Trial Data.
Diabetes. 68(6):1267-1276 [DOI] 10.2337/db19-0057. [PMID] 30967424.
2019
Metabolite-related dietary patterns and the development of islet autoimmunity
Scientific Reports. 9(1) [DOI] 10.1038/s41598-019-51251-4. [PMID] 31616039.
2019
Objectively Measured Adherence in Adolescents With Type 1 Diabetes on Multiple Daily Injections and Insulin Pump Therapy.
Journal of pediatric psychology. 44(1):21-31 [DOI] 10.1093/jpepsy/jsy064. [PMID] 30184209.
2019
Predicting progression to type 1 diabetes from ages 3 to 6 in islet autoantibody positive TEDDY children
Pediatric Diabetes. 20(3):263-270 [DOI] 10.1111/pedi.12812. [PMID] 30628751.
2019
Prospective virome analyses in young children at increased genetic risk for type 1 diabetes.
Nature medicine. 25(12):1865-1872 [DOI] 10.1038/s41591-019-0667-0. [PMID] 31792456.
2019
Relative Pancreas Volume Is Reduced in First-Degree Relatives of Patients With Type 1 Diabetes.
Diabetes care. 42(2):281-287 [DOI] 10.2337/dc18-1512. [PMID] 30552130.
2019
The association between stressful life events and respiratory infections during the first 4 years of life: The Environmental Determinants of Diabetes in the Young study
Stress and Health. 35(3):289-303 [DOI] 10.1002/smi.2861. [PMID] 30768831.
2018
Application of a Genetic Risk Score to Racially Diverse Type 1 Diabetes Populations Demonstrates the Need for Diversity in Risk-Modeling.
Scientific reports. 8(1) [DOI] 10.1038/s41598-018-22574-5. [PMID] 29540798.
2018
Growth hormone and insulin-like growth factor-I axis in type 1 diabetes.
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society. 38:49-52 [DOI] 10.1016/j.ghir.2017.12.005. [PMID] 29249623.
2018
Hospital time prior to death and pancreas histopathology: implications for future studies.
Diabetologia. 61(4):954-958 [DOI] 10.1007/s00125-017-4494-x. [PMID] 29128936.
2018
Immune Intervention for Type 1 Diabetes.
Diabetes technology & therapeutics. 20(S1):S86-S93 [DOI] 10.1089/dia.2018.2507. [PMID] 29437480.
2018
Low-Dose Anti-Thymocyte Globulin (ATG) Preserves β-Cell Function and Improves HbA1c in New-Onset Type 1 Diabetes.
Diabetes care. 41(9):1917-1925 [DOI] 10.2337/dc18-0494. [PMID] 30012675.
2018
Pancreatic Histopathology of Human Monogenic Diabetes Due to Causal Variants in KCNJ11, HNF1A, GATA6, and LMNA.
The Journal of clinical endocrinology and metabolism. 103(1):35-45 [DOI] 10.1210/jc.2017-01159. [PMID] 28938416.
2018
Strength in Numbers: Opportunities for Enhancing the Development of Effective Treatments for Type 1 Diabetes-The TrialNet Experience.
Diabetes. 67(7):1216-1225 [DOI] 10.2337/db18-0065. [PMID] 29769238.
2018
The Environmental Determinants of Diabetes in the Young (TEDDY) Study: 2018 Update.
Current diabetes reports. 18(12) [DOI] 10.1007/s11892-018-1113-2. [PMID] 30353256.
2018
Transition Education for Young Adults With Type 1 Diabetes: Pilot Feasibility Study for a Group Telehealth Intervention.
JMIR diabetes. 3(4) [DOI] 10.2196/10909. [PMID] 30401674.
2018
Type 1 Diabetes in Children and Adolescents: A Position Statement by the American Diabetes Association.
Diabetes care. 41(9):2026-2044 [DOI] 10.2337/dci18-0023. [PMID] 30093549.
2018
Understanding Pre-Type 1 Diabetes: The Key to Prevention.
Frontiers in endocrinology. 9 [DOI] 10.3389/fendo.2018.00070. [PMID] 29559955.
2017
Association Between Early-Life Antibiotic Use and the Risk of Islet or Celiac Disease Autoimmunity.
JAMA pediatrics. 171(12):1217-1225 [DOI] 10.1001/jamapediatrics.2017.2905. [PMID] 29052687.
2017
Differentiation of Diabetes by Pathophysiology, Natural History, and Prognosis.
Diabetes. 66(2):241-255 [DOI] 10.2337/db16-0806. [PMID] 27980006.
2017
Effect of Oral Insulin on Prevention of Diabetes in Relatives of Patients With Type 1 Diabetes: A Randomized Clinical Trial.
JAMA. 318(19):1891-1902 [DOI] 10.1001/jama.2017.17070. [PMID] 29164254.
2017
Erratum. 2016 Presidential Address: Diabetes at 212°-Confronting the Invisible Disease. Diabetes Care 2016;39:1657-1663.
Diabetes care. 40(5) [DOI] 10.2337/dc17-er05a. [PMID] 28302650.
2017
Factors That Influence the Quality of RNA From the Pancreas of Organ Donors.
Pancreas. 46(2):252-259 [DOI] 10.1097/MPA.0000000000000717. [PMID] 27984510.
2017
High Illicit Drug Abuse and Suicide in Organ Donors With Type 1 Diabetes.
Diabetes care. 40(9):e122-e123 [DOI] 10.2337/dc17-0996. [PMID] 28679687.
2017
Immune Interventions for Type 1 Diabetes Mellitus.
Diabetes technology & therapeutics. 19(S1):S74-S81 [DOI] 10.1089/dia.2017.2507. [PMID] 28192018.
2017
Intake of Energy and Protein is Associated with Overweight Risk at Age 5.5 Years: Results from the Prospective TEDDY Study.
Obesity (Silver Spring, Md.). 25(8):1435-1441 [DOI] 10.1002/oby.21897. [PMID] 28650578.
2017
More on Intralymphatic Injection of Autoantigen in Type 1 Diabetes.
The New England journal of medicine. 377(4) [DOI] 10.1056/NEJMc1703468. [PMID] 28748691.
2017
My Child Is Islet Autoantibody Positive: Impact on Parental Anxiety.
Diabetes care. 40(9):1167-1172 [DOI] 10.2337/dc17-0166. [PMID] 28663383.
2017
Plant-based vaccines for oral delivery of type 1 diabetes-related autoantigens: Evaluating oral tolerance mechanisms and disease prevention in NOD mice.
Scientific reports. 7 [DOI] 10.1038/srep42372. [PMID] 28205558.
2017
Poor Adherence to Ketone Testing in Patients With Type 1 Diabetes.
Diabetes care. 40(4):e38-e39 [DOI] 10.2337/dc16-2620. [PMID] 28100607.
2017
Serum Trypsinogen Levels in Type 1 Diabetes.
Diabetes care. 40(4):577-582 [DOI] 10.2337/dc16-1774. [PMID] 28115475.
2017
Tracking the Antibody Immunome in Type 1 Diabetes Using Protein Arrays.
Journal of proteome research. 16(1):195-203 [DOI] 10.1021/acs.jproteome.6b00354. [PMID] 27690455.
2017
Type 1 diabetes mellitus.
Nature reviews. Disease primers. 3 [DOI] 10.1038/nrdp.2017.16. [PMID] 28358037.
2016
2016 Presidential Address: Diabetes at 212°-Confronting the Invisible Disease.
Diabetes care. 39(10):1657-63 [DOI] 10.2337/dc16-1558. [PMID] 27660119.
2016
Antithymocyte Globulin Plus G-CSF Combination Therapy Leads to Sustained Immunomodulatory and Metabolic Effects in a Subset of Responders With Established Type 1 Diabetes.
Diabetes. 65(12):3765-3775 [PMID] 27669730.
View on: PubMed
2016
C-peptide levels in pediatric type 2 diabetes in the Pediatric Diabetes Consortium T2D Clinic Registry.
Pediatric diabetes. 17(4):274-80 [DOI] 10.1111/pedi.12280. [PMID] 25940861.
2016
Characteristics of youth with type 1 diabetes (T1D) with and without a parent with T1D in the T1D exchange clinic registry.
Journal of diabetes. 8(6):834-838 [DOI] 10.1111/1753-0407.12363. [PMID] 26663683.
2016
Complement gene variants in relation to autoantibodies to beta cell specific antigens and type 1 diabetes in the TEDDY Study.
Scientific reports. 6 [DOI] 10.1038/srep27887. [PMID] 27306948.
2016
Current and future efforts toward the prevention of type 1 diabetes.
Pediatric diabetes. 17 Suppl 22:78-86 [DOI] 10.1111/pedi.12333. [PMID] 27411441.
2016
Diagnostic Dilemma: Clinical and Histological Abnormalities in a Hispanic Patient With Diabetes.
Diabetes care. 39(9):1650-2 [DOI] 10.2337/dc16-0711. [PMID] 27555624.
2016
Educational Needs and Technological Preferences of Fathers of Youth With Type 1 Diabetes.
The Diabetes educator. 42(2):209-19 [DOI] 10.1177/0145721716628649. [PMID] 26850045.
2016
Glucagon Nasal Powder: A Promising Alternative to Intramuscular Glucagon in Youth With Type 1 Diabetes.
Diabetes care. 39(4):555-62 [DOI] 10.2337/dc15-1606. [PMID] 26884472.
2016
Hemoglobin A1c (HbA1c) changes over time among adolescent and young adult participants in the T1D exchange clinic registry.
Pediatric diabetes. 17(5):327-36 [DOI] 10.1111/pedi.12295. [PMID] 26153338.
2016
HLA-DRB1*15:01-DQA1*01:02-DQB1*06:02 Haplotype Protects Autoantibody-Positive Relatives From Type 1 Diabetes Throughout the Stages of Disease Progression.
Diabetes. 65(4):1109-19 [DOI] 10.2337/db15-1105. [PMID] 26822082.
2016
Identification of tissue-specific cell death using methylation patterns of circulating DNA.
Proceedings of the National Academy of Sciences of the United States of America. 113(13):E1826-34 [DOI] 10.1073/pnas.1519286113. [PMID] 26976580.
2016
Immune Intervention in Type 1 Diabetes.
Diabetes technology & therapeutics. 18 Suppl 1:S69-75 [DOI] 10.1089/dia.2016.2507. [PMID] 26836431.
2016
Immunoproteomic Profiling of Antiviral Antibodies in New-Onset Type 1 Diabetes Using Protein Arrays.
Diabetes. 65(1):285-96 [DOI] 10.2337/db15-0179. [PMID] 26450993.
2016
Insulitis and β-Cell Mass in the Natural History of Type 1 Diabetes.
Diabetes. 65(3):719-31 [DOI] 10.2337/db15-0779. [PMID] 26581594.
2016
Mobilization without immune depletion fails to restore immunological tolerance or preserve beta cell function in recent onset type 1 diabetes.
Clinical and experimental immunology. 183(3):350-7 [DOI] 10.1111/cei.12731. [PMID] 26462724.
2016
Pancreatic duct hyperplasia/dysplasia in type 1 diabetes and pancreatic weight in individuals with and without diabetes. Reply to Kobayashi T, Aida K, Fukui T et al [letter] and Saisho Y [letter].
Diabetologia. 59(4):870-2 [DOI] 10.1007/s00125-016-3889-4. [PMID] 26861059.
2016
Presumptive Type 1 Diabetes With Comorbidities and Rapid Progression Despite Numerous Insulin-Positive Islets.
Diabetes care. 39(7):1292-4 [DOI] 10.2337/dc16-0737. [PMID] 27330131.
2016
Reevaluation of CMS’ Competitive Bidding Program.
Diabetes care. 39(7):1078-9 [DOI] 10.2337/dc16-0903. [PMID] 27330123.
2016
Reversion of β-Cell Autoimmunity Changes Risk of Type 1 Diabetes: TEDDY Study.
Diabetes care. 39(9):1535-42 [DOI] 10.2337/dc16-0181. [PMID] 27311490.
2016
The DIPP project: 20 years of discovery in type 1 diabetes.
Pediatric diabetes. 17 Suppl 22:5-7 [DOI] 10.1111/pedi.12398. [PMID] 27411430.
2016
The influence of type 1 diabetes on pancreatic weight.
Diabetologia. 59(1):217-221 [DOI] 10.1007/s00125-015-3752-z. [PMID] 26358584.
2016
Towards a functional hypothesis relating anti-islet cell autoimmunity to the dietary impact on microbial communities and butyrate production.
Microbiome. 4 [DOI] 10.1186/s40168-016-0163-4. [PMID] 27114075.
2016
Type 1 diabetes through two lenses: comparing adolescent and parental perspectives with photovoice.
International journal of pediatric endocrinology. 2016 [DOI] 10.1186/s13633-016-0020-z. [PMID] 26793242.
2016
Validation of a rapid type 1 diabetes autoantibody screening assay for community-based screening of organ donors to identify subjects at increased risk for the disease.
Clinical and experimental immunology. 185(1):33-41 [DOI] 10.1111/cei.12797. [PMID] 27029857.
2016
Vitamin D status in youth with type 1 and type 2 diabetes enrolled in the Pediatric Diabetes Consortium (PDC) is not worse than in youth without diabetes.
Pediatric diabetes. 17(8):584-591 [DOI] 10.1111/pedi.12340. [PMID] 26611890.
2015
Acute Versus Progressive Onset of Diabetes in NOD Mice: Potential Implications for Therapeutic Interventions in Type 1 Diabetes.
Diabetes. 64(11):3885-90 [DOI] 10.2337/db15-0449. [PMID] 26216853.
2015
Anti-thymocyte globulin/G-CSF treatment preserves β cell function in patients with established type 1 diabetes.
The Journal of clinical investigation. 125(1):448-55 [DOI] 10.1172/JCI78492. [PMID] 25500887.
2015
Body mass index changes in youth in the first year after type 1 diabetes diagnosis.
The Journal of pediatrics. 166(5):1265-1269.e1 [DOI] 10.1016/j.jpeds.2015.02.036. [PMID] 25919735.
2015
Combination Therapy Reverses Hyperglycemia in NOD Mice With Established Type 1 Diabetes.
Diabetes. 64(11):3873-84 [DOI] 10.2337/db15-0164. [PMID] 26185279.
2015
Defining pathways for development of disease-modifying therapies in children with type 1 diabetes: a consensus report.
Diabetes care. 38(10):1975-85 [DOI] 10.2337/dc15-1429. [PMID] 26404927.
2015
Disparities in social support systems for youths with type 1 diabetes.
Clinical diabetes : a publication of the American Diabetes Association. 33(2):62-9 [DOI] 10.2337/diaclin.33.2.62. [PMID] 25897185.
2015
Early childhood gut microbiomes show strong geographic differences among subjects at high risk for type 1 diabetes.
Diabetes care. 38(2):329-32 [DOI] 10.2337/dc14-0850. [PMID] 25519450.
2015
Erratum: Disparities in Social Support for Youths With Type 1 Diabetes. Clinical Diabetes 2015;33:62-69.
Clinical diabetes : a publication of the American Diabetes Association. 33(3) [DOI] 10.2337/diaclin.33.3.159. [PMID] 26202839.
2015
Lowering targets for hemoglobin A1c in children with type 1 diabetes: raising the bar.
Pediatric diabetes. 16(1):16-21 [DOI] 10.1111/pedi.12244. [PMID] 25394220.
2015
Predictors of Progression From the Appearance of Islet Autoantibodies to Early Childhood Diabetes: The Environmental Determinants of Diabetes in the Young (TEDDY).
Diabetes care. 38(5):808-13 [DOI] 10.2337/dc14-2426. [PMID] 25665818.
2015
Puppy Love, Adolescence, and Chronic Illness: The Importance of Pets for Youth with Type 1 Diabetes.
Journal of patient experience. 2(1):21-24 [DOI] 10.1177/237437431500200105. [PMID] 28725812.
2015
Rates of diabetic ketoacidosis: international comparison with 49,859 pediatric patients with type 1 diabetes from England, Wales, the U.S., Austria, and Germany.
Diabetes care. 38(10):1876-82 [DOI] 10.2337/dc15-0780. [PMID] 26283737.
2015
Role of Type 1 Diabetes-Associated SNPs on Risk of Autoantibody Positivity in the TEDDY Study.
Diabetes. 64(5):1818-29 [DOI] 10.2337/db14-1497. [PMID] 25422107.
2015
Screening for T1D risk to reduce DKA is not economically viable.
Pediatric diabetes. 16(8):565-72 [DOI] 10.1111/pedi.12313. [PMID] 26392298.
2015
Staging presymptomatic type 1 diabetes: a scientific statement of JDRF, the Endocrine Society, and the American Diabetes Association.
Diabetes care. 38(10):1964-74 [DOI] 10.2337/dc15-1419. [PMID] 26404926.
2015
The 6 year incidence of diabetes-associated autoantibodies in genetically at-risk children: the TEDDY study.
Diabetologia. 58(5):980-7 [DOI] 10.1007/s00125-015-3514-y. [PMID] 25660258.
2015
Using photography as a method to explore adolescent challenges and resilience in type 1 diabetes.
Diabetes spectrum : a publication of the American Diabetes Association. 28(2):92-8 [DOI] 10.2337/diaspect.28.2.92. [PMID] 25987807.
2014
9β Polymorphism of the glucocorticoid receptor gene appears to have limited impact in patients with Addison’s disease.
PloS one. 9(1) [DOI] 10.1371/journal.pone.0086350. [PMID] 24466047.
2014
A contrast between children and adolescents with excellent and poor control: the T1D Exchange clinic registry experience.
Pediatric diabetes. 15(2):110-7 [DOI] 10.1111/pedi.12067. [PMID] 23957219.
2014
B-lymphocyte depletion with rituximab and β-cell function: two-year results.
Diabetes care. 37(2):453-9 [DOI] 10.2337/dc13-0626. [PMID] 24026563.
2014
Bacteroides dorei dominates gut microbiome prior to autoimmunity in Finnish children at high risk for type 1 diabetes.
Frontiers in microbiology. 5 [DOI] 10.3389/fmicb.2014.00678. [PMID] 25540641.
2014
Cardiovascular risk factors in patients with Addison’s disease: a comparative study of South African and Swedish patients.
PloS one. 9(6) [DOI] 10.1371/journal.pone.0090768. [PMID] 24603607.
2014
Compromised gut microbiota networks in children with anti-islet cell autoimmunity.
Diabetes. 63(6):2006-14 [DOI] 10.2337/db13-1676. [PMID] 24608442.
2014
Costimulation modulation with abatacept in patients with recent-onset type 1 diabetes: follow-up 1 year after cessation of treatment.
Diabetes care. 37(4):1069-75 [DOI] 10.2337/dc13-0604. [PMID] 24296850.
2014
Diabetes and employment.
Diabetes care. 37 Suppl 1:S112-7 [DOI] 10.2337/dc14-S112. [PMID] 24357206.
2014
Distribution of C-peptide and its determinants in North American children at risk for type 1 diabetes.
Diabetes care. 37(7):1959-65 [DOI] 10.2337/dc13-2603. [PMID] 24760262.
2014
Effect of a single autologous cord blood infusion on beta-cell and immune function in children with new onset type 1 diabetes: a non-randomized, controlled trial.
Pediatric diabetes. 15(2):100-9 [DOI] 10.1111/pedi.12072. [PMID] 24102806.
2014
Healthcare transition from pediatric to adult medical homes in diabetes mellitus.
Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists. 20(7):715-21 [DOI] 10.4158/EP13369.RA. [PMID] 24449671.
2014
HLA similarities indicate shared genetic risk in 21-hydroxylase autoantibody positive South African and United States Addison’s disease.
Tissue antigens. 84(4):361-9 [DOI] 10.1111/tan.12407. [PMID] 25040682.
2014
IgG4 antibodies in autoimmune polyglandular disease and IgG4-related endocrinopathies: pathophysiology and clinical characteristics.
Current opinion in pediatrics. 26(4):493-9 [DOI] 10.1097/MOP.0000000000000107. [PMID] 24905103.
2014
Insulin pump use in young children in the T1D Exchange clinic registry is associated with lower hemoglobin A1c levels than injection therapy.
Pediatric diabetes. 15(8):564-72 [DOI] 10.1111/pedi.12121. [PMID] 24494980.
2014
Pump Use Is Less Frequent in Minority Youth: Transatlantic Analysis in Three Large Registries Representing Austria, Germany, England, Wales and the United States
. 57(1)
2014
The Juvenile Diabetes Research Foundation Network for Pancreatic Organ Donors with Diabetes (nPOD) Program: goals, operational model and emerging findings.
Pediatric diabetes. 15(1):1-9 [DOI] 10.1111/pedi.12097. [PMID] 24325575.
2014
Workplace Checkup: Keeping Patients With Diabetes Employed and Safe on the Job.
Clinical diabetes : a publication of the American Diabetes Association. 32(1):44-8 [DOI] 10.2337/diaclin.32.1.44. [PMID] 26246678.
2013
Autologous umbilical cord blood infusion followed by oral docosahexaenoic acid and vitamin D supplementation for C-peptide preservation in children with Type 1 diabetes.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. 19(7):1126-9 [DOI] 10.1016/j.bbmt.2013.04.011. [PMID] 23611977.
2013
Body mass index at the time of diagnosis of autoimmune type 1 diabetes in children.
The Journal of pediatrics. 162(4):736-740.e1 [DOI] 10.1016/j.jpeds.2012.09.017. [PMID] 23092524.
2013
Diabetes and employment.
Diabetes care. 36 Suppl 1:S93-7 [DOI] 10.2337/dc13-S093. [PMID] 23264429.
2013
Diabetes care in the school and day care setting.
Diabetes care. 36 Suppl 1:S75-9 [DOI] 10.2337/dc13-S075. [PMID] 23264426.
2013
Ethnicity influences the diagnosis of primary adrenal insufficiency.
Clinical endocrinology. 78(5):800-2 [DOI] 10.1111/cen.12063. [PMID] 23051632.
2013
Increased cardiovascular risk in South African patients with Addison’s disease.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. 45(12):905-10 [DOI] 10.1055/s-0033-1351259. [PMID] 23918685.
2013
Increased complement activation in human type 1 diabetes pancreata.
Diabetes care. 36(11):3815-7 [DOI] 10.2337/dc13-0203. [PMID] 24041678.
2013
Interleukin-1 antagonism in type 1 diabetes of recent onset: two multicentre, randomised, double-blind, placebo-controlled trials.
Lancet (London, England). 381(9881):1905-15 [DOI] 10.1016/S0140-6736(13)60023-9. [PMID] 23562090.
2013
Investigation of glucocorticoid receptor polymorphisms in relation to metabolic parameters in Addison’s disease.
European journal of endocrinology. 168(3):403-12 [DOI] 10.1530/EJE-12-0808. [PMID] 23239757.
2013
Proposal for generating new beta cells in a muted immune environment for type 1 diabetes.
Diabetes/metabolism research and reviews. 29(8):604-6 [DOI] 10.1002/dmrr.2435. [PMID] 23853103.
2013
Race and Socioeconomic Status Are Associated With Insulin Pump Therapy in Youth in the First Year Following Diagnosis of Type 1 Diabetes
Diabetes Technology & Therapeutics. 15:A25-A26
2013
Race, socioeconomic status, and treatment center are associated with insulin pump therapy in youth in the first year following diagnosis of type 1 diabetes.
Diabetes technology & therapeutics. 15(11):929-34 [DOI] 10.1089/dia.2013.0132. [PMID] 23869706.
2013
Salivary cortisol day curves in Addison’s disease in patients on hydrocortisone replacement.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. 45(1):62-8 [DOI] 10.1055/s-0032-1321855. [PMID] 22893258.
2013
Serological autoantibody profiling of type 1 diabetes by protein arrays.
Journal of proteomics. 94:486-96 [DOI] 10.1016/j.jprot.2013.10.018. [PMID] 24148850.
2013
The autoimmune disease-associated SNP rs917997 of IL18RAP controls IFNγ production by PBMC.
Journal of autoimmunity. 44:8-12 [DOI] 10.1016/j.jaut.2013.06.001. [PMID] 23891168.
2013
The prediction of type 1 diabetes by multiple autoantibody levels and their incorporation into an autoantibody risk score in relatives of type 1 diabetic patients.
Diabetes care. 36(9):2615-20 [DOI] 10.2337/dc13-0425. [PMID] 23818528.
2012
Diabetes and employment.
Diabetes care. 35 Suppl 1:S94-8 [DOI] 10.2337/dc12-s094. [PMID] 22187477.
2012
Diabetes care in the school and day care setting.
Diabetes care. 35 Suppl 1:S76-80 [DOI] 10.2337/dc12-s076. [PMID] 22187474.
2012
Network for Pancreatic Organ Donors with Diabetes (nPOD): developing a tissue biobank for type 1 diabetes.
Diabetes/metabolism research and reviews. 28(7):608-17 [DOI] 10.1002/dmrr.2316. [PMID] 22585677.
2012
Performance of HbA1c as an early diagnostic indicator of type 1 diabetes in children and youth.
Diabetes care. 35(9):1821-5 [PMID] 22699293.
View on: PubMed
2012
The use of leptin as treatment for type 1 diabetes mellitus: counterpoint.
Pediatric diabetes. 13(1):74-6 [DOI] 10.1111/j.1399-5448.2011.00796.x. [PMID] 21884562.
2012
Through the fog: recent clinical trials to preserve β-cell function in type 1 diabetes.
Diabetes. 61(6):1323-30 [DOI] 10.2337/db11-1452. [PMID] 22618767.
2012
Update on global intervention studies in type 1 diabetes.
Endocrinology and metabolism clinics of North America. 41(4):695-712 [DOI] 10.1016/j.ecl.2012.07.003. [PMID] 23099265.
2011
A longitudinal study of GAD65 and ICA512 autoantibodies during the progression to type 1 diabetes in Diabetes Prevention Trial-Type 1 (DPT-1) participants.
Diabetes care. 34(11):2435-7 [DOI] 10.2337/dc11-0981. [PMID] 21911777.
2011
Antigen-based therapy with glutamic acid decarboxylase (GAD) vaccine in patients with recent-onset type 1 diabetes: a randomised double-blind trial.
Lancet (London, England). 378(9788):319-27 [DOI] 10.1016/S0140-6736(11)60895-7. [PMID] 21714999.
2011
Autoimmune markers in diabetes.
Clinical chemistry. 57(2):168-75 [DOI] 10.1373/clinchem.2010.148205. [PMID] 21127152.
2011
Autologous umbilical cord blood transfusion in young children with type 1 diabetes fails to preserve C-peptide.
Diabetes care. 34(12):2567-9 [DOI] 10.2337/dc11-1406. [PMID] 22011412.
2011
Co-stimulation modulation with abatacept in patients with recent-onset type 1 diabetes: a randomised, double-blind, placebo-controlled trial.
Lancet (London, England). 378(9789):412-9 [DOI] 10.1016/S0140-6736(11)60886-6. [PMID] 21719096.
2011
Country-specific birth weight and length in type 1 diabetes high-risk HLA genotypes in combination with prenatal characteristics.
Journal of perinatology : official journal of the California Perinatal Association. 31(12):764-9 [DOI] 10.1038/jp.2011.26. [PMID] 21527903.
2011
Development of autoantibodies in the TrialNet Natural History Study.
Diabetes care. 34(9):1897-901 [DOI] 10.2337/dc11-0560. [PMID] 21750277.
2011
Gut microbiome metagenomics analysis suggests a functional model for the development of autoimmunity for type 1 diabetes.
PloS one. 6(10) [DOI] 10.1371/journal.pone.0025792. [PMID] 22043294.
2011
Islet autoantibody seroconversion in the DPT-1 study: justification for repeat screening throughout childhood.
Diabetes care. 34(2):358-62 [DOI] 10.2337/dc10-1494. [PMID] 21270193.
2011
It’s time to mow the GRAS in type 1 diabetes.
Diabetes. 60(11):2669-71 [DOI] 10.2337/db11-1158. [PMID] 22025772.
2011
Long-term outcome of individuals treated with oral insulin: diabetes prevention trial-type 1 (DPT-1) oral insulin trial.
Diabetes care. 34(7):1585-90 [DOI] 10.2337/dc11-0523. [PMID] 21610124.
2011
Progressive erosion of β-cell function precedes the onset of hyperglycemia in the NOD mouse model of type 1 diabetes.
Diabetes. 60(8):2086-91 [DOI] 10.2337/db11-0373. [PMID] 21659497.
2011
Reduced serum vitamin D-binding protein levels are associated with type 1 diabetes.
Diabetes. 60(10):2566-70 [DOI] 10.2337/db11-0576. [PMID] 21844098.
2011
The pancreas in human type 1 diabetes.
Seminars in immunopathology. 33(1):29-43 [DOI] 10.1007/s00281-010-0208-x. [PMID] 20495921.
2011
Toward defining the autoimmune microbiome for type 1 diabetes.
The ISME journal. 5(1):82-91 [DOI] 10.1038/ismej.2010.92. [PMID] 20613793.
2011
Use of a precious resource: parental decision making about using autologous umbilical cord blood in studies involving young children with type 1 diabetes.
Contemporary clinical trials. 32(4):524-9 [DOI] 10.1016/j.cct.2011.04.004. [PMID] 21530680.
2010
Autoimmunity predominates in a large South African cohort with Addison’s disease of mainly European descent despite long-standing disease and is associated with HLA DQB*0201.
Clinical endocrinology. 73(3):291-8 [DOI] 10.1111/j.1365-2265.2010.03807.x. [PMID] 20455895.
2010
Butyrate and type 1 diabetes mellitus: can we fix the intestinal leak?
Journal of pediatric gastroenterology and nutrition. 51(4):414-7 [DOI] 10.1097/MPG.0b013e3181dd913a. [PMID] 20706153.
2010
Efforts to prevent and halt autoimmune beta cell destruction.
Endocrinology and metabolism clinics of North America. 39(3):527-39 [DOI] 10.1016/j.ecl.2010.05.006. [PMID] 20723818.
2010
Enhancing the understanding of pre-type 1 diabetes in the general population.
Diabetes care. 33(6):1403-5 [DOI] 10.2337/dc10-0566. [PMID] 20508234.
2010
Estimating the cost of type 1 diabetes in the U.S.: a propensity score matching method.
PloS one. 5(7) [DOI] 10.1371/journal.pone.0011501. [PMID] 20634976.
2010
Exendin-4 treatment of nonobese diabetic mice increases beta-cell proliferation and fractional insulin reactive area.
Journal of diabetes and its complications. 24(3):163-7 [DOI] 10.1016/j.jdiacomp.2008.12.004. [PMID] 19217320.
2010
Failure to preserve beta-cell function with mycophenolate mofetil and daclizumab combined therapy in patients with new- onset type 1 diabetes.
Diabetes care. 33(4):826-32 [DOI] 10.2337/dc09-1349. [PMID] 20067954.
2010
Harmonization of glutamic acid decarboxylase and islet antigen-2 autoantibody assays for national institute of diabetes and digestive and kidney diseases consortia.
The Journal of clinical endocrinology and metabolism. 95(7):3360-7 [DOI] 10.1210/jc.2010-0293. [PMID] 20444913.
2010
Intradermal alpha1-antitrypsin therapy avoids fatal anaphylaxis, prevents type 1 diabetes and reverses hyperglycaemia in the NOD mouse model of the disease.
Diabetologia. 53(10):2198-204 [DOI] 10.1007/s00125-010-1829-2. [PMID] 20593162.
2010
Lactobacillus johnsonii N6.2 mitigates the development of type 1 diabetes in BB-DP rats.
PloS one. 5(5) [DOI] 10.1371/journal.pone.0010507. [PMID] 20463897.
2010
The Pediatric Diabetes Consortium: Improving Care of Children With Type 1 Diabetes Through Collaborative Research
Diabetes Technology & Therapeutics. 12(9):685-688 [DOI] 10.1089/dia.2010.0065. [PMID] 20687862.
2010
Type I diabetes. Preface.
Endocrinology and metabolism clinics of North America. 39(3):xvii-xviii [DOI] 10.1016/j.ecl.2010.05.012. [PMID] 20723814.
2009
Autologous nonmyeloablative hematopoietic stem cell transplantation in newly diagnosed type 1 diabetes mellitus.
JAMA. 302(6):624; author reply 624-5 [DOI] 10.1001/jama.2009.1098. [PMID] 19671901.
2009
Autologous umbilical cord blood transfusion in very young children with type 1 diabetes.
Diabetes care. 32(11):2041-6 [DOI] 10.2337/dc09-0967. [PMID] 19875605.
2009
Challenges in developing endpoints for type 1 diabetes intervention studies.
Diabetes/metabolism research and reviews. 25(8):694-704 [DOI] 10.1002/dmrr.1002. [PMID] 19771545.
2009
Culture-independent identification of gut bacteria correlated with the onset of diabetes in a rat model.
The ISME journal. 3(5):536-48 [DOI] 10.1038/ismej.2009.5. [PMID] 19225551.
2009
Immune depletion with cellular mobilization imparts immunoregulation and reverses autoimmune diabetes in nonobese diabetic mice.
Diabetes. 58(10):2277-84 [DOI] 10.2337/db09-0557. [PMID] 19628781.
2009
Influence of fecal sample storage on bacterial community diversity.
The open microbiology journal. 3:40-6 [DOI] 10.2174/1874285800903010040. [PMID] 19440250.
2009
Influence of membrane CD25 stability on T lymphocyte activity: implications for immunoregulation.
PloS one. 4(11) [DOI] 10.1371/journal.pone.0007980. [PMID] 19956753.
2009
Network for Pancreatic Organ Donors With Diabetes (Npod): Donor Demographics and Early Progress Report
Hormone Research. 72:156-157
2009
Pancreatic adenocarcinoma patients with localised chronic severe pancreatitis show an increased number of single beta cells, without alterations in fractional insulin area.
Diabetologia. 52(2):262-70 [DOI] 10.1007/s00125-008-1200-z. [PMID] 19002428.
2009
Pancreatic islet autoantibodies as predictors of type 1 diabetes in the Diabetes Prevention Trial-Type 1.
Diabetes care. 32(12):2269-74 [DOI] 10.2337/dc09-0934. [PMID] 19741189.
2009
Participant and parent experiences in the oral insulin study of the Diabetes Prevention Trial for Type 1 Diabetes.
Pediatric diabetes. 10(3):177-83 [DOI] 10.1111/j.1399-5448.2008.00463.x. [PMID] 18823410.
2009
Rituximab, B-lymphocyte depletion, and preservation of beta-cell function.
The New England journal of medicine. 361(22):2143-52 [DOI] 10.1056/NEJMoa0904452. [PMID] 19940299.
2009
Seroconversion in the Dpt-1 Study: Evidence of Triggering of Autoimmune Process At Different Ages
. 52
2009
The road not taken: a path to curing type 1 diabetes?
European journal of immunology. 39(8):2054-8 [DOI] 10.1002/eji.200939517. [PMID] 19672902.
2009
Vitamin D levels in subjects with and without type 1 diabetes residing in a solar rich environment.
Diabetes care. 32(11):1977-9 [DOI] 10.2337/dc09-1089. [PMID] 19675194.
2008
Autologous umbilical cord blood infusion for type 1 diabetes.
Experimental hematology. 36(6):710-5 [DOI] 10.1016/j.exphem.2008.01.009. [PMID] 18358588.
2008
CFTR mutations impart elevated immune reactivity in a murine model of cystic fibrosis related diabetes.
Cytokine. 44(1):154-9 [DOI] 10.1016/j.cyto.2008.07.468. [PMID] 18778952.
2008
Cytokines and type 1 diabetes complications: casual or causal association?
Pediatric diabetes. 9(1):1-2 [DOI] 10.1111/j.1399-5448.2007.00364.x. [PMID] 18211629.
2008
Exendin-4 therapy in NOD mice with new-onset diabetes increases regulatory T cell frequency.
Annals of the New York Academy of Sciences. 1150:152-6 [DOI] 10.1196/annals.1447.049. [PMID] 19120286.
2008
Human alpha 1-antitrypsin therapy induces fatal anaphylaxis in non-obese diabetic mice.
Clinical and experimental immunology. 154(1):15-21 [DOI] 10.1111/j.1365-2249.2008.03721.x. [PMID] 18759852.
2008
Murine antithymocyte globulin therapy alters disease progression in NOD mice by a time-dependent induction of immunoregulation.
Diabetes. 57(2):405-14 [PMID] 18039815.
View on: PubMed
2008
Neonatal formula feeding leads to immunological alterations in an animal model of type 1 diabetes.
Pediatric research. 63(3):303-7 [PMID] 18091354.
View on: PubMed
2008
The IDS conducts standardization of assays for the measurement of autoantibodies and of T cells in autoimmune diabetes. Preface.
Annals of the New York Academy of Sciences. 1150 [DOI] 10.1196/annals.1447.066. [PMID] 19120260.
2008
The rosigliazone meta-analysis: lessons for the future.
Diabetes care. 31(3) [DOI] 10.2337/dc07-2147. [PMID] 18308673.
2008
Type 1 diabetes associated with acquired generalized lipodystrophy and insulin resistance: the effect of long-term leptin therapy.
The Journal of clinical endocrinology and metabolism. 93(1):26-31 [PMID] 17940115.
View on: PubMed
2008
What’s in a name? Thyroid autoimmunity in obese patients with T1D.
Pediatric diabetes. 9(4 Pt 1):263-5 [DOI] 10.1111/j.1399-5448.2008.00368.x. [PMID] 18768034.
2007
Adverse impact of temperature and humidity on blood glucose monitoring reliability: a pilot study.
Diabetes technology & therapeutics. 9(1):1-9 [PMID] 17316092.
View on: PubMed
2007
Comment on: Brugman S et al. (2006) Antibiotic treatment partially protects against type 1 diabetes in the Bio-Breeding diabetes-prone rat. Is the gut flora involved in the development of type 1 diabetes? Diabetologia 49:2105-2108.
Diabetologia. 50(1):220-1 [PMID] 17119915.
View on: PubMed
2007
Endocrine complications of childhood cancer therapy: evaluation and management.
Pediatric endocrinology reviews : PER. 4(3):196-204 [PMID] 17551480.
View on: PubMed
2007
No alterations in the frequency of FOXP3+ regulatory T-cells in type 1 diabetes.
Diabetes. 56(3):604-12 [PMID] 17327427.
View on: PubMed
2007
Participant and parent experiences in the parenteral insulin arm of the diabetes prevention trial for type 1 diabetes.
Diabetes care. 30(9):2193-8 [PMID] 17563348.
View on: PubMed
2007
Peripheral artery tonometry demonstrates altered endothelial function in children with type 1 diabetes.
Pediatric diabetes. 8(4):193-8 [PMID] 17659060.
View on: PubMed
2007
Persistence of high health care expenditures among children in Medicaid.
Medical care research and review : MCRR. 64(3):304-30 [PMID] 17507460.
View on: PubMed
2007
Type 1 diabetes intervention trials 2007: where are we and where are we going?
Current opinion in endocrinology, diabetes, and obesity. 14(4):283-7 [PMID] 17940453.
View on: PubMed
2006
Assessing the utility of SELDI-TOF and model averaging for serum proteomic biomarker discovery.
Proteomics. 6(24):6405-15 [PMID] 17096316.
View on: PubMed
2006
Cystic fibrosis transmembrane conductance regulator deficiency exacerbates islet cell dysfunction after beta-cell injury.
Diabetes. 55(7):1939-45 [PMID] 16804061.
View on: PubMed
2006
Maternal understanding of infant diabetes risk: differential effects of maternal anxiety and depression.
Genetics in medicine : official journal of the American College of Medical Genetics. 8(10):665-70 [PMID] 17079884.
View on: PubMed
2006
Specific human leukocyte antigen DQ influence on expression of antiislet autoantibodies and progression to type 1 diabetes.
The Journal of clinical endocrinology and metabolism. 91(5):1705-13 [PMID] 16464953.
View on: PubMed
2006
The application of genomic and proteomic technologies in predictive, preventive and personalized medicine.
Vascular pharmacology. 45(5):258-67 [PMID] 17030152.
View on: PubMed
2005
Autoimmunity to glutamic acid decarboxylase in the neurodegenerative disorder Batten disease.
Neurology. 64(4):743-5 [PMID] 15728308.
View on: PubMed
2005
CD3-antibody therapy in new-onset type 1 diabetes mellitus.
The New England journal of medicine. 353(19):2086-7; author reply 2086 [PMID] 16282188.
View on: PubMed
2005
Changes in intestinal morphology and permeability in the biobreeding rat before the onset of type 1 diabetes.
Journal of pediatric gastroenterology and nutrition. 40(5):589-95 [PMID] 15861021.
View on: PubMed
2005
Depressive symptoms in mothers of infants identified as genetically at risk for type 1 diabetes.
Diabetes care. 28(8):1898-903 [PMID] 16043729.
View on: PubMed
2005
Ecological implications of the emergence of non-toxic subcultures from toxic Microcystis strains.
Environmental microbiology. 7(6):798-805 [PMID] 15892699.
View on: PubMed
2005
Functional defects and the influence of age on the frequency of CD4+ CD25+ T-cells in type 1 diabetes.
Diabetes. 54(5):1407-14 [PMID] 15855327.
View on: PubMed
2005
High frequency of abnormal glucose tolerance in DQA1*0102/DQB1*0602 relatives identified as part of the Diabetes Prevention Trial–Type 1 Diabetes.
Diabetologia. 48(1):68-74 [PMID] 15602651.
View on: PubMed
2005
Islet cell autoantibodies: a case of a premature obituary.
Pediatric diabetes. 6(4):181-3 [PMID] 16390385.
View on: PubMed
2005
Lack of correlation between the levels of soluble cytotoxic T-lymphocyte associated antigen-4 (CTLA-4) and the CT-60 genotypes.
Journal of autoimmune diseases. 2 [DOI] 10.1186/1740-2557-2-8. [PMID] 16259622.
2005
Managed care organization characteristics and outpatient specialty care use among children with chronic illness.
Pediatrics. 115(6):1547-54 [PMID] 15930215.
View on: PubMed
2005
Maternal efforts to prevent type 1 diabetes in at-risk children.
Diabetes care. 28(4):916-21 [PMID] 15793195.
View on: PubMed
2005
The role of leuprolide acetate therapy in triggering auto-immune thyroiditis.
The Journal of pediatrics. 146(2):294; author reply 294-5 [PMID] 15689930.
View on: PubMed
2005
Type 1 diabetes mellitus: etiology, presentation, and management.
Pediatric clinics of North America. 52(6):1553-78 [PMID] 16301083.
View on: PubMed
2004
Adiponectin and leptin concentrations may aid in discriminating disease forms in children and adolescents with type 1 and type 2 diabetes.
Diabetes care. 27(8):2010-4 [PMID] 15277432.
View on: PubMed
2004
Blood lymphocyte chimerism associated with IVF and monochorionic dizygous twinning: case report.
Human reproduction (Oxford, England). 19(12):2816-21 [PMID] 15375077.
View on: PubMed
2004
Diabetes care at diabetes camps.
Diabetes care. 27 Suppl 1:S129-31 [PMID] 14693947.
View on: PubMed
2004
Diabetes care in the school and day care setting.
Diabetes care. 27 Suppl 1:S122-8 [PMID] 14693946.
View on: PubMed
2004
Islet replacement vs. regeneration: hope or hype?
Pediatric diabetes. 5 Suppl 2:45-56 [PMID] 15601374.
View on: PubMed
2004
Maternal anxiety associated with newborn genetic screening for type 1 diabetes.
Diabetes care. 27(2):392-7 [PMID] 14747219.
View on: PubMed
2004
Oral insulin therapy to prevent progression of immune-mediated (type 1) diabetes.
Annals of the New York Academy of Sciences. 1029:260-77 [PMID] 15681764.
View on: PubMed
2004
Preservation of C-peptide secretion in subjects at high risk of developing type 1 diabetes mellitus–a new surrogate measure of non-progression?
Pediatric diabetes. 5(2):72-9 [PMID] 15189492.
View on: PubMed
2003
Aberrant monocyte prostaglandin synthase 2 (PGS2) expression in type 1 diabetes before and after disease onset.
Pediatric diabetes. 4(1):10-8 [PMID] 14655518.
View on: PubMed
2003
Care of children with diabetes in the school and day care setting.
Diabetes care. 26 Suppl 1:S131-5 [PMID] 12502641.
View on: PubMed
2003
Management of diabetes at diabetes camps.
Diabetes care. 26 Suppl 1:S136-8 [PMID] 12502642.
View on: PubMed
2003
Multiple autoantibodies as predictors of Type 1 diabetes in a general population.
Diabetologia. 46(6):873-4 [PMID] 12802500.
View on: PubMed
2003
Overview of prevention and intervention trials for type 1 diabetes.
Reviews in endocrine & metabolic disorders. 4(4):317-23 [PMID] 14618016.
View on: PubMed
2003
Prevention strategies for type 1 diabetes mellitus: current status and future directions.
BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy. 17(1):39-64 [PMID] 12534319.
View on: PubMed
2003
Prospective assessment in newborns of diabetes autoimmunity (PANDA): maternal understanding of infant diabetes risk.
Genetics in medicine : official journal of the American College of Medical Genetics. 5(2):77-83 [PMID] 12644776.
View on: PubMed
2003
Screening strategies for the identification of multiple antibody-positive relatives of individuals with type 1 diabetes.
The Journal of clinical endocrinology and metabolism. 88(1):103-8 [PMID] 12519837.
View on: PubMed
2003
Vaccine therapies for the prevention of type 1 diabetes mellitus.
Paediatric drugs. 5(9):575-82 [PMID] 12956615.
View on: PubMed
2003
Why can’t we prevent type 1 diabetes?: maybe it’s time to try a different combination.
Diabetes care. 26(12):3326-8 [PMID] 14633822.
View on: PubMed
2002
Autoimmune polyglandular syndrome. II: Clinical syndrome and treatment.
Endocrinology and metabolism clinics of North America. 31(2):339-52 [PMID] 12092454.
View on: PubMed
2002
Generation of islets of Langerhans from adult pancreatic stem cells.
Journal of hepato-biliary-pancreatic surgery. 9(6):704-9 [PMID] 12658404.
View on: PubMed
2002
Prospects for the prevention and reversal of type 1 diabetes mellitus.
Drugs. 62(18):2617-35 [PMID] 12466001.
View on: PubMed
2002
To screen or not to screen for pre-type 1 diabetes?
Hormone research. 57 Suppl 1:12-7 [PMID] 11979016.
View on: PubMed
2002
Type 1 diabetes islet autoantibody markers.
Diabetes technology & therapeutics. 4(6):817-39 [PMID] 12614488.
View on: PubMed
2002
Use of in vitro-generated, stem cell-derived islets to cure type 1 diabetes: how close are we?
Annals of the New York Academy of Sciences. 958:59-68 [PMID] 12021084.
View on: PubMed
2001
First-phase insulin release during the intravenous glucose tolerance test as a risk factor for type 1 diabetes.
The Journal of pediatrics. 138(2):244-9 [PMID] 11174623.
View on: PubMed
2001
Intervention to delay the onset of diabetes mellitus in very young siblings of children with type 1 diabetes mellitus.
Journal of pediatric endocrinology & metabolism : JPEM. 14 Suppl 1:623-6 [PMID] 11393554.
View on: PubMed
2001
Pancreatic stem cells: a therapeutic agent that may offer the best approach for curing type 1 diabetes.
Pediatric diabetes. 2(4):195-202 [PMID] 15016187.
View on: PubMed
2001
Prediction and prevention of type 1 diabetes.
Current diabetes reports. 1(1):28-32 [PMID] 12762954.
View on: PubMed
2001
Proposed guidelines on screening for risk of type 1 diabetes.
Diabetes care. 24(2) [PMID] 11213898.
View on: PubMed
2001
Update on major trials for the prevention of type 1 diabetes mellitus: the American Diabetes Prevention Trial (DPT-1) and the European Nicotinamide Diabetes Intervention Trial (ENDIT).
Journal of pediatric endocrinology & metabolism : JPEM. 14 Suppl 1:619-22 [PMID] 11393553.
View on: PubMed
2000
Glutamic acid decarboxylase and IA-2 autoantibodies in type 1 diabetes: comparing sample substrates for autoantibody determinations.
Pediatric diabetes. 1(1):10-6 [PMID] 15016237.
View on: PubMed
2000
Islet cell antibody-positive relatives with human leukocyte antigen DQA1*0102, DQB1*0602: identification by the Diabetes Prevention Trial-type 1.
The Journal of clinical endocrinology and metabolism. 85(3):1255-60 [PMID] 10720072.
View on: PubMed
2000
Reversal of insulin-dependent diabetes using islets generated in vitro from pancreatic stem cells.
Nature medicine. 6(3):278-82 [PMID] 10700229.
View on: PubMed
2000
The relationship of maternal personality characteristics to birth outcomes and infant development.
Birth (Berkeley, Calif.). 27(1):25-32 [PMID] 10865557.
View on: PubMed
2000
Therapeutic controversy: prevention and treatment of diabetes in children.
The Journal of clinical endocrinology and metabolism. 85(2):494-522 [PMID] 10690847.
View on: PubMed
1999
Aberrant prostaglandin synthase 2 expression defines an antigen-presenting cell defect for insulin-dependent diabetes mellitus.
The Journal of clinical investigation. 104(4):515-23 [PMID] 10449443.
View on: PubMed
1999
Cellular immune responses against proinsulin: no evidence for enhanced reactivity in individuals with IDDM.
Diabetes. 48(2):299-303 [PMID] 10334305.
View on: PubMed
1999
Only multiple autoantibodies to islet cells (ICA), insulin, GAD65, IA-2 and IA-2beta predict immune-mediated (Type 1) diabetes in relatives.
Journal of autoimmunity. 12(4):279-87 [PMID] 10330299.
View on: PubMed
1999
The prevention of type I diabetes mellitus.
Pediatric annals. 28(9):585-8 [PMID] 10496000.
View on: PubMed
1998
A putative HCO3- transporter in the cyanobacterium Synechococcus sp. strain PCC 7942.
FEBS letters. 430(3):236-40 [PMID] 9688546.
View on: PubMed
1998
Aging and the immune response to tetanus toxoid: diminished frequency and level of cellular immune reactivity to antigenic stimulation.
Clinical and diagnostic laboratory immunology. 5(6):894-6 [PMID] 9801353.
View on: PubMed
1998
Cellular immune responses to beta casein: elevated in but not specific for individuals with Type I diabetes mellitus.
Diabetologia. 41(6):731-5 [PMID] 9662058.
View on: PubMed
1998
Extreme Th1 bias of invariant Valpha24JalphaQ T cells in type 1 diabetes.
Nature. 391(6663):177-81 [PMID] 9428763.
View on: PubMed
1998
Patient and family reflections on the use of subcutaneous insulin to prevent diabetes: a retrospective evaluation from a pilot prevention trial.
Journal of diabetes and its complications. 12(5):279-86 [PMID] 9747645.
View on: PubMed
1998
The relationship between humoral and cellular immunity to IA-2 in IDDM.
Diabetes. 47(4):566-9 [PMID] 9568688.
View on: PubMed
1997
Pharmacological approaches to the prevention of autoimmune diabetes.
Drugs. 53(6):943-56 [PMID] 9179526.
View on: PubMed
1996
Although DR3-DQB1*0201 may be associated with multiple component diseases of the autoimmune polyglandular syndromes, the human leukocyte antigen DR4-DQB1*0302 haplotype is implicated only in beta-cell autoimmunity.
The Journal of clinical endocrinology and metabolism. 81(7):2559-63 [PMID] 8675578.
View on: PubMed
1996
Antigen based therapies to prevent diabetes in NOD mice.
Journal of autoimmunity. 9(3):349-56 [PMID] 8816970.
View on: PubMed
1996
Autoantibodies to the extracellular domain of the calcium sensing receptor in patients with acquired hypoparathyroidism.
The Journal of clinical investigation. 97(4):910-4 [PMID] 8613543.
View on: PubMed
1996
Cow’s milk and insulin-dependent diabetes mellitus. Innocent until proven guilty.
JAMA. 276(8):647-8 [PMID] 8773639.
View on: PubMed
1996
Prevention of insulin-dependent diabetes mellitus: an overview of three trials.
Cleveland Clinic journal of medicine. 63(5):270-4 [PMID] 8870337.
View on: PubMed
1995
Accuracy of self-monitoring blood glucose meters in a high humidity, high temperature summer camp setting.
Diabetes care. 18(8):1200-1 [PMID] 7587863.
View on: PubMed
1995
Age and family relationship accentuate the risk of insulin-dependent diabetes mellitus (IDDM) in relatives of patients with IDDM.
The Journal of clinical endocrinology and metabolism. 80(12):3739-43 [PMID] 8530627.
View on: PubMed
1995
Prevention of insulin-dependent diabetes-1995.
Trends in endocrinology and metabolism: TEM. 6(9-10):312-7 [PMID] 18406716.
View on: PubMed
1995
Recent advances in the immunopathogenesis of insulin-dependent diabetes mellitus.
Current opinion in pediatrics. 7(4):459-65 [PMID] 7581652.
View on: PubMed
1995
Testosterone induced priapism in two adolescents with sickle cell disease.
Journal of pediatric endocrinology & metabolism : JPEM. 8(3):199-203 [PMID] 8521195.
View on: PubMed
1994
Diabetic ketoacidosis in childhood.
Pediatric annals. 23(6):284-8 [PMID] 8078704.
View on: PubMed
1994
Fatal parathyroid hormone-related protein-induced humoral hypercalcemia of malignancy in a 3-month-old infant.
European journal of pediatrics. 153(10):718-20 [PMID] 7813527.
View on: PubMed
1994
GAD65 autoantibodies increase the predictability but not the sensitivity of islet cell and insulin autoantibodies for developing insulin dependent diabetes mellitus.
Journal of autoimmunity. 7(6):865-72 [PMID] 7888042.
View on: PubMed
1994
Glycemic control in a sample of black and white clinic patients with NIDDM.
Diabetes care. 17(10):1148-53 [PMID] 7821134.
View on: PubMed
1994
High risk HLA-DR/DQ genotypes for IDD confer susceptibility to autoantibodies but DQB1*0602 does not prevent them.
Journal of autoimmunity. 7(6):889-97 [PMID] 7888045.
View on: PubMed
1994
Hypoglycemia in childhood diabetes.
Pediatric annals. 23(6):289-91 [PMID] 8078705.
View on: PubMed
1994
Islet cell antibodies predict insulin-dependent diabetes in United States school age children as powerfully as in unaffected relatives.
The Journal of clinical investigation. 93(6):2403-7 [PMID] 8200974.
View on: PubMed
1993
Antigen-specific immunotherapy: oral tolerance and subcutaneous immunization in the treatment of insulin-dependent diabetes.
Diabetes/metabolism reviews. 9(4):279-87 [PMID] 7924825.
View on: PubMed
1993
Autoimmune Addison’s disease.
Springer seminars in immunopathology. 14(3):275-84 [PMID] 8438210.
View on: PubMed
1993
Early diagnosis and specific treatment of insulin-dependent diabetes.
Annals of the New York Academy of Sciences. 696:342-50 [PMID] 8109841.
View on: PubMed
1993
Insulin and islet cell autoantibodies as time-dependent covariates in the development of insulin-dependent diabetes: a prospective study in relatives.
The Journal of clinical endocrinology and metabolism. 77(3):743-9 [PMID] 8370696.
View on: PubMed
1993
Intervention therapies for insulin-dependent diabetes.
Autoimmunity. 16(4):301-10 [PMID] 8025209.
View on: PubMed
1993
Permanent diabetes developing after transient neonatal diabetes.
Lancet (London, England). 341(8852) [PMID] 8096989.
View on: PubMed
1993
The genetics of autoimmune diabetes. Approaching a solution to the problem.
American journal of diseases of children (1960). 147(12):1282-90 [PMID] 8249945.
View on: PubMed
1992
Human anti-pneumococcal polysaccharide antibodies are secreted by the CD5- B cell lineage.
Cellular immunology. 143(1):66-79 [PMID] 1377990.
View on: PubMed
1992
Permanent diabetes without serological evidence of autoimmunity after transient neonatal diabetes.
Diabetes care. 15(10):1273-6 [PMID] 1425088.
View on: PubMed
1992
The pathogenesis, prediction, and prevention of insulin-dependent diabetes mellitus.
Endocrinology and metabolism clinics of North America. 21(2):199-219 [PMID] 1612064.
View on: PubMed
1991
CD5+ B lymphocytes in high-risk islet cell antibody-positive and newly diagnosed IDDM subjects.
Diabetes. 40(10):1314-8 [PMID] 1718800.
View on: PubMed
1991
Defective inducer T-cell function before the onset of insulin-dependent diabetes mellitus.
Journal of autoimmunity. 4(1):125-36 [PMID] 1827712.
View on: PubMed
1991
Increased T lymphocytes bearing the gamma-delta T cell receptor in subjects at high risk for insulin dependent diabetes.
Journal of autoimmunity. 4(6):925-33 [PMID] 1839880.
View on: PubMed
1991
Selective expression of RAG-2 in chicken B cells undergoing immunoglobulin gene conversion.
Cell. 64(1):201-208 [DOI] 10.1016/0092-8674(91)90221-J. [PMID] 1986866.
1991
Successful in utero treatment of fetal goiter and hypothyroidism.
The New England journal of medicine. 324(8):543-6 [PMID] 1992308.
View on: PubMed
1991
The parental origin of the single X chromosome in Turner syndrome: lack of correlation with parental age or clinical phenotype.
American journal of human genetics. 48(4):682-6 [PMID] 1673045.
View on: PubMed
1990
A prospective study of the development of diabetes in relatives of patients with insulin-dependent diabetes.
The New England journal of medicine. 323(17):1167-72 [PMID] 2215594.
View on: PubMed
1990
Comparison of islet autoantibodies in ‘pre-diabetes’ and recommendations for screening.
Journal of autoimmunity. 3 Suppl 1:47-51 [PMID] 2187460.
View on: PubMed
1990
Minimizing risk of brain herniation during treatment of diabetic ketoacidemia.
The Journal of pediatrics. 117(6):1009-10 [PMID] 2123238.
View on: PubMed
1990
Relationship of autoimmunity to thyroid dysfunction in children and adults with Down syndrome.
American journal of medical genetics. Supplement. 7:238-41 [PMID] 2149955.
View on: PubMed
1990
Scientific writing courses for pediatrics fellows.
Academic medicine : journal of the Association of American Medical Colleges. 65(10):652-3 [PMID] 2261045.
View on: PubMed
1989
Initial pathogenic events in IDDM.
Diabetes. 38(4):534-8 [PMID] 2647560.
View on: PubMed
1989
Long-term immunoregulatory effects of therapy with corticosteroids and anti-thymocyte globulin.
Immunopharmacology and immunotoxicology. 11(2-3):269-87 [PMID] 2695566.
View on: PubMed
1989
Natural history of incidental hyperglycemia and glycosuria of childhood.
The Journal of pediatrics. 115(5 Pt 1):676-80 [PMID] 2681635.
View on: PubMed
1988
Lymphocyte subsets in pre-diabetes.
Advances in experimental medicine and biology. 246:109-14 [PMID] 3074645.
View on: PubMed
1988
Polyclonal nature of islet cell antibodies in insulin-dependent diabetes.
Autoimmunity. 1(1):45-50 [PMID] 2979605.
View on: PubMed
1987
Evolution of the subclass of IgG antibody to type 3 pneumococcal polysaccharide during childhood.
Clinical and experimental immunology. 70(2):449-55 [PMID] 3427829.
View on: PubMed

Grants

Sep 2021 ACTIVE
Natural History and Mechanisms of Exocrine Pancreatic Dysfunction in Pre-Type 1 Diabetes
Role: Other
Funding: NATL INST OF HLTH NIDDK
May 2021 ACTIVE
The Network for Pancreatic Organ donors with Diabetes (nPOD) : A Collaborative Type 1 Diabetes Research Project
Role: Project Manager
Funding: HELMSLEY CHARITABLE TRUST, LEONA & HARRY
Oct 2020 ACTIVE
Data Coordinating Center for the Consortium for Identification of Environmental Determinants of Diabetes in the Young (TEDDY) Study.
Role: Principal Investigator
Funding: AUGUSTA UNIVERSITY via NATL INST OF HLTH NIDDK
Aug 2020 ACTIVE
Understanding pancreatic endocrine and exocrine loss in pre-type 1 diabetes
Role: Co-Investigator
Funding: NATL INST OF HLTH NIDDK
Feb 2020 ACTIVE
Human Atlas of Neonatal Developmental and Early Life Pancreas / Immunity (HANDEL)-P/I Continuation
Role: Co-Investigator
Funding: HELMSLEY CHARITABLE TRUST, LEONA & HARRY
Feb 2020 ACTIVE
TrialNet Clinical Center infrastructure support services
Role: Co-Investigator
Funding: UNIV OF SOUTH FLORIDA via NATL INST OF HLTH NIDDK
Jan 2020 – Apr 2021
Mechanisms of Exocrine Dysfunction in Type 1 Diabetes
Role: Other
Funding: PEDIATRIC ENDOCRINE SOCIETY
Jan 2020 ACTIVE
Mechanisms of Exocrine Dysfunction in Type 1 Diabetes
Role: Other
Funding: ENDOCRINE FELLOWS FOU
Dec 2019 ACTIVE
MED202 – Regional Perinatal Intensive Care Centers Program (RPICC) Data System FY19-21
Role: Principal Investigator
Funding: AGCY FOR HLTH CARE ADMN via US DEPT OF HLTH AND HUMAN SER
Jul 2019 ACTIVE
Early Steps Data Systems Operation (ESDS) – COQXV
Role: Principal Investigator
Funding: FL DEPT OF HLTH CHILDRENS MED SERVS via US DEPT OF EDUCATION
Jul 2019 – Jun 2020
TrialNet Affiliate Services
Role: Principal Investigator
Funding: UNIV OF SOUTH FLORIDA via NATL INST OF HLTH NIDDK
Apr 2019 – Sep 2020
Data Coordinating Center for the Consortium for Identification of Environmental Determinants of Diabetes in the Young (TEDDY)
Role: Principal Investigator
Funding: AUGUSTA UNIVERSITY via NATL INST OF HLTH NIDDK
Nov 2018 – Oct 2019
Collaborative Research Group – Diabetes and Obesity
Role: Principal Investigator
Funding: UNIV OF NORTH CAROLINA CHAPEL HILL via PATIENT-CENTERED OUTCOMES RES INST
Sep 2018 – May 2020
Use of MD Logic Automated Insulin Delivery System: Safety and Efficacy
Role: Principal Investigator
Funding: HEALTHPARTNERS INST FOR EDU AND RES via NATL INST OF HLTH NIDDK
Sep 2018 – Aug 2021
Identification of Anti-Neo-Antigen AutoAntibodies in Type 1 Diabetes
Role: Co-Investigator
Funding: ARIZONA STATE UNIVERSITY via NATL INST OF HLTH NIDDK
Sep 2018 ACTIVE
The TEDDY Study: Georgia/Florida Clinical Center
Role: Principal Investigator
Funding: AUGUSTA UNIVERSITY via NATL INST OF HLTH NIDDK
Jul 2018 ACTIVE
Regenerative Medicine Training Grant
Role: Co-Investigator
Funding: NATL INST OF HLTH NIDDK
Jul 2018 – Jun 2019
TrialNet Affiliate Services
Role: Principal Investigator
Funding: UNIV OF SOUTH FLORIDA via NATL INST OF HLTH NIDDK
Jun 2018 ACTIVE
Immune Function and the Progression to Type 1 Diabetes
Role: Co-Investigator
Funding: NATL INST OF HLTH NIAID
Jun 2018 – Aug 2018
Data Coordinating Center for the Consortium for Identificaiton of Environmental Determinants of Diabetes in the Young (TEDDY) Study (GAP Funding)
Role: Principal Investigator
Funding: AUGUSTA UNIVERSITY via NATL INST OF HLTH NIDDK
Apr 2018 ACTIVE
FLDOH CMS Disease Management Contract – COQWY: Pediatric Pulmonary Center Training Program – Family Support
Role: Principal Investigator
Funding: FL DEPT OF HLTH CHILDRENS MED SERVS via US HLTH RESOURCES AND SERV ADMN
Apr 2018 ACTIVE
Network for Pancreatic Organ Donors – nPOD
Role: Co-Investigator
Funding: JDRF
Apr 2018 – Jul 2019
Together: Transforming and Translating Discovery to Improve Health
Role: Other
Funding: NATL INST OF HLTH NCATS
Apr 2018 – Mar 2019
Data Coordinating Center for the Consortium for Identification of Environmental Determinants of Diabetes In the Young (TEDDY) "Study"
Role: Principal Investigator
Funding: AUGUSTA UNIVERSITY via NATL INST OF HLTH NIDDK
Jan 2018 ACTIVE
Regional Perinatal Intensive Care Center (RPICC)
Role: Principal Investigator
Funding: FL DEPT OF HLTH CHILDRENS MED SERVS
Jan 2018 – Mar 2021
Collaborative Type 1 Diabetes Research Project: The Network for Pancreatic Organ donors with Diabetes (nPOD)
Role: Co-Investigator
Funding: HELMSLEY CHARITABLE TRUST, LEONA & HARRY
Sep 2017 ACTIVE
Non-invasive detection of cell death in type 1 diabetes: insight into novel disease mechanisms.
Role: Principal Investigator
Funding: NATL INST OF HLTH NIDDK
Aug 2017 – Jul 2018
Low-Dose IL-2 in Established T1D
Role: Principal Investigator
Funding: UNIV OF MIAMI via NATL INST OF HLTH NIAID
Jul 2017 – Jul 2022
Evaluation of the DreaMed Advice4U for Automated Insulin Pump Settings Adjustments in Children and Adolescents with Type 1 Diabetes.
Role: Principal Investigator
Funding: SCHNEIDER CHILDRENS MED CTR OF ISRAEL via HELMSLEY CHARITABLE TRUST, LEONA & HARRY
Jul 2017 – Jun 2018
TrialNet Affiliate Services FY 17-18
Role: Principal Investigator
Funding: UNIV OF SOUTH FLORIDA via NATL INST OF HLTH NIDDK
Apr 2017 – Mar 2018
Together: Transforming and Translating Discovery to Improve Health
Role: Faculty
Funding: NATL INST OF HLTH NCATS
Jan 2017 – Oct 2018
Diabetes and Obesity Collaborative Research Group
Role: Principal Investigator
Funding: VANDERBILT UNIVERSITY MEDICAL CENTER via PATIENT-CENTERED OUTCOMES RES INST
Sep 2016 – Sep 2018
Home Use of MD-Logic Automated Insulin Delivery System: Safety and Efficacy.
Role: Principal Investigator
Funding: HEALTHPARTNERS INST FOR EDU AND RES via NATL INST OF HLTH NIDDK
Jul 2016 ACTIVE
CMS Newborn Screening – COQWX
Role: Principal Investigator
Funding: FL DEPT OF HLTH CHILDRENS MED SERVS
Jul 2016 ACTIVE
SHANDS Teaching Hospital Award Program (CMN)
Role: Principal Investigator
Funding: UF HEALTH SHANDS CHILDRENS HOSPITAL
Jul 2016 ACTIVE
FLDOH CMS Disease Management Contract – COQWY
Role: Principal Investigator
Funding: FL DEPT OF HLTH CHILDRENS MED SERVS
Jul 2016 – Jun 2017
TrialNet Affiliate Services
Role: Principal Investigator
Funding: UNIV OF SOUTH FLORIDA via NATL INST OF HLTH
Jun 2016 – May 2018
Reimbursement Payments for Physicians Efforts.
Role: Principal Investigator
Funding: AUGUSTA UNIVERSITY via NATL INST OF HLTH
Oct 2015 – Jun 2019
Early Steps Data System Operation (ESDS)
Role: Principal Investigator
Funding: FL DEPT OF HLTH CHILDRENS MED SERVS via US DEPT OF EDUCATION
Jul 2015 – Jun 2016
Trialnet affiliate services
Role: Principal Investigator
Funding: UNIV OF SOUTH FLORIDA
Jun 2015 – May 2016
Reimbursement Payments for Physicians Efforts
Role: Principal Investigator
Funding: *GEORGIA REGENTS UNIVERSITY via NATL INST OF HLTH
Feb 2015 – Jun 2019
MED 164 – Regional Perinatal Intensive Care Centers Program (RPICC) Date System
Role: Principal Investigator
Funding: AGCY FOR HLTH CARE ADMN via US DEPT OF HLTH AND HUMAN SER
Jan 2015 – Dec 2019
Pediatric Salary Support Fund – Srivastava Lab
Role: Principal Investigator
Funding: UF FOUNDATION
Sep 2014 – Aug 2018
Non-invasive diagnosis of human beta cell damage and death
Role: Principal Investigator
Funding: NATL INST OF HLTH NIDDK
Sep 2014 – Jan 2020
EXTEND – Preserving Beta-Cell Function with Tocilizumab in new Onset Type 1 Diabetes
Role: Principal Investigator
Funding: BENAROYA RES INST AT VA MASON via NATL INST OF HLTH NIAID
Jun 2014 – Apr 2020
TrialNet: University of Florida Clinical Center and Network
Role: Project Manager
Funding: NATL INST OF HLTH NIDDK
Jun 2013 – May 2018
Consortium for Identification of Environmental Triggers
Role: Principal Investigator
Funding: GEORGIA HLTH SCIENCES UNIV via NATL INST OF HLTH NIDDK
May 2013 – Jun 2018
Immune Function and the Progression to Type 1 Diabetes
Role: Project Manager
Funding: NATL INST OF HLTH NIAID
Aug 2012 – Mar 2018
A randomized, double-blind, multiple dose, placebocontrolled study to evaluate the safety, tolerability, immunogenicity, pharmacokinetics, and efficacy of secukinumab in adult and pediatric patients with new-onset type 1 diabetes mellitus (T1D)
Role: Principal Investigator
Funding: NOVARTIS US
Aug 2012 – Dec 2020
New Areas of Research
Role: Principal Investigator
Funding: UF FOUNDATION
Oct 2010 – Mar 2019
T1D Exchange Type 1 Diabetes Network
Role: Principal Investigator
Funding: JAEB CTR FOR HLTH RES via HELMSLEY CHARITABLE TRUST, LEONA & HARRY
Jul 2007 ACTIVE
DOH/CMS Admin Fee Supporting Dept of Pediatrics
Role: Principal Investigator
Funding: UF DIV OF SPONSORED RESEARCH
Nov 2005 – Dec 2020
Children's Research Initiative
Role: Principal Investigator
Funding: UF FOUNDATION

Patents

Issued October 2016
Lactobacillus Supplement for Alleviating Type I Diabetes
#9,474,773
Published January 2016
Type 1 Diabetes Biomarkers
#US-2016-0195546-A1
Published May 2008
Materials and Methods for Reversing Type I Diabetes
#US-2009-0162345-A1

Education

Fellowship – Pediatric Endocrinology
1989 · University of Florida
Residency – Pediatrics
1986 · University of Florida
Internship – Pediatrics
1984 · University of Florida
Bachelor of Medicine, Bachelor of Surgery
1979 · University of Witwatersrand

Teaching Profile

Courses Taught
2018
MDT7400 Elect Top/Pediatrics
2018
MDC7400 Pediatric Clerkship

Contact Details

Phones:
Business:
(352) 273-9270
Emails:
Business:
schatz@ufl.edu