Laura Jacobsen, M.D.
Assistant Professor
About Laura Jacobsen
Laura Jacobsen, MD, is an assistant professor and pediatric endocrinologist who joined the University of Florida faculty in 2018 in the department of pediatrics. She completed her pediatric residency training at the University of North Carolina in Chapel Hill, which was followed by a pediatric endocrinology fellowship at the UF Health Shands Children’s Hospital in Gainesville, Florida. During her fellowship, Dr. Jacobsen was recognized for her excellence in medical student teaching, and she received the Henry A. Kokomoor Outstanding Fellowship Award.
Dr. Jacobsen provides clinical care for children with endocrine disorders and diabetes. She performs clinical and translational research in the field of Type 1 diabetes to better understand what causes Type 1 diabetes and ways to halt or prevent it.
Dr. Jacobsen is conversational in American Sign Language.
Accomplishments
Excellence in Medical Student Education Pediatric Clerkship Rotation
2019
·
UF Department of Pediatrics
Henry A. Kokomoor Outstanding Fellowship Award
2017
·
UF Department of Pediatrics
Type 1 Diabetes TrialNet Emerging Leader
2017
·
Type 1 Diabetes TrialNet
Floyd W. Denny Pediatric Society Resident Award for Excellence in Pediatric Care
2015
·
UNC Department of Pediatrics
Johnny Carson Award for Best Overall Research Evening of Scholarship
2015
·
UNC Department of Pediatrics
UF Chapman Chapter of the Gold Humanism Honor Society Inductee
2011
·
UF College of Medicine
Teaching Profile
Courses Taught
2018
MDC7400 Pediatric Clerkship
2018
MDT7090 Elective Topics
2018
MDC6001 Intro Clin Practice
Board Certifications
-
Pediatric EndocrinologyAmerican Board of Pediatrics
-
PediatricsAmerican Board of Pediatrics
Clinical Profile
Specialties
- Pediatrics
Subspecialties
- Pediatric Endocrinology
Areas of Interest
- Blood glucose monitoring
- Pediatric pituitary and skull base services
- Type 1 diabetes
- Type 2 diabetes
Research Profile
Areas of Interest
- Diabetes Technology
- Immunology of Type 1 diabetes
- Prevention and intervention trials in Type 1 diabetes
- Type 1 Diabetes
Open Researcher and Contributor ID (ORCID)
0000-0002-5144-7836
Publications
2022
Accuracy of Three Commercial Home-Use HbA1c Tests.
Diabetes technology & therapeutics.
[DOI] 10.1089/dia.2022.0187.
[PMID] 35763337.
2022
Age and Hospitalization Risk in People With Type 1 Diabetes and COVID-19: Data From the T1D Exchange Surveillance Study.
The Journal of clinical endocrinology and metabolism.
107(2):410-418
[DOI] 10.1210/clinem/dgab668.
[PMID] 34581790.
2022
Cost-Effectiveness of Low-Dose Antithymocyte Globulin Versus Other Immunotherapies for Treatment of New-Onset Type 1 Diabetes
Diabetes Technology & Therapeutics.
24(4):258-267
[DOI] 10.1089/dia.2021.0329.
2022
Factors Associated With Achieving Target A1C in Children and Adolescents With Type 1 Diabetes: Findings From the T1D Exchange Quality Improvement Collaborative
Clinical Diabetes.
[DOI] 10.2337/cd22-0073.
2022
Heterogeneity of DKA Incidence and Age-Specific Clinical Characteristics in Children Diagnosed With Type 1 Diabetes in the TEDDY Study
Diabetes Care.
45(3):624-633
[DOI] 10.2337/dc21-0422.
[PMID] 35043162.
2022
Hybrid Closed-Loop Systems and Glycemic Outcomes in Children and Adults With Type 1 Diabetes: Real-World Evidence From a U.S.-Based Multicenter Collaborative.
Diabetes care.
45(8):e118-e119
[DOI] 10.2337/dc22-0329.
[PMID] 35708494.
2022
Index60 Identifies Individuals at Appreciable Risk for Stage 3 Among an Autoantibody-Positive Population With Normal 2-Hour Glucose Levels: Implications for Current Staging Criteria of Type 1 Diabetes.
Diabetes care.
45(2):311-318
[DOI] 10.2337/dc21-0944.
[PMID] 34853027.
2022
Index60 Is Superior to HbA1c for Identifying Individuals at High Risk for Type 1 Diabetes
The Journal of Clinical Endocrinology & Metabolism.
[DOI] 10.1210/clinem/dgac440.
2021
A retrospective multisite examination of depression screening practices, scores, and correlates in pediatric diabetes care.
Translational behavioral medicine.
11(1):122-131
[DOI] 10.1093/tbm/ibz171.
[PMID] 31764981.
2021
Adherence to oral glucose tolerance testing in children in stage 1 of type 1 diabetes: The
TEDDY
study
Pediatric Diabetes.
22(2):360-368
[DOI] 10.1111/pedi.13149.
[PMID] 33179853.
2021
Barriers to retinopathy screening in youth and young adults with type 1 diabetes
Pediatric Diabetes.
22(3):469-473
[DOI] 10.1111/pedi.13171.
2021
How Do We Move Type 1 Diabetes Immunotherapies Forward During the Current COVID-19 Pandemic?
Diabetes.
70(5):1021-1028
[DOI] 10.2337/dbi20-0045.
[PMID] 33632743.
2021
Index60 as an additional diagnostic criterion for type 1 diabetes.
Diabetologia.
64(4):836-844
[DOI] 10.1007/s00125-020-05365-4.
[PMID] 33496819.
2021
Insulin immunotherapy for pretype 1 diabetes.
Current opinion in endocrinology, diabetes, and obesity.
28(4):390-396
[DOI] 10.1097/MED.0000000000000648.
[PMID] 34091488.
2021
Low-Dose ATG/GCSF in Established Type 1 Diabetes: A Five-Year Follow-up Report
Diabetes.
70(5):1123-1129
[DOI] 10.2337/db20-1103.
[PMID] 33632742.
2021
Monogenic Diabetes and Integrated Stress Response Genes Display Altered Gene Expression in Type 1 Diabetes
Diabetes.
70(8):1885-1897
[DOI] 10.2337/db21-0070.
[PMID] 34035041.
2021
Multisite Examination of Depression Screening Scores and Correlates Among Adolescents and Young Adults With Type 2 Diabetes
Canadian Journal of Diabetes.
45(5):411-416
[DOI] 10.1016/j.jcjd.2021.01.011.
[PMID] 33722492.
2021
Real-World Screening for Retinopathy in Youth With Type 1 Diabetes Using a Nonmydriatic Fundus Camera
Diabetes Spectrum.
34(1):27-33
[DOI] 10.2337/ds20-0017.
[PMID] 33627991.
2021
Substance Use Affects Type 1 Diabetes Pancreas Pathology: Implications for Future Studies.
Frontiers in endocrinology.
12
[DOI] 10.3389/fendo.2021.778912.
[PMID] 34912300.
2020
A Novel Mutation in Insulin-Like Growth Factor 1 Receptor (c.641-2A>G) Is Associated with Impaired Growth, Hypoglycemia, and Modified Immune Phenotypes
Hormone Research in Paediatrics.
93(5):322-334
[DOI] 10.1159/000510764.
[PMID] 33113547.
2020
Comparing Beta Cell Preservation Across Clinical Trials in Recent-Onset Type 1 Diabetes.
Diabetes technology & therapeutics.
22(12):948-953
[DOI] 10.1089/dia.2020.0305.
[PMID] 32833543.
2020
Erratum. Who Is Enrolling? The Path to Monitoring in Type 1 Diabetes TrialNet’s Pathway to Prevention. Diabetes Care 2019;42:2228-2236.
Diabetes care.
43(4)
[DOI] 10.2337/dc20-er04.
[PMID] 32132004.
2020
Histological validation of a type 1 diabetes clinical diagnostic model for classification of diabetes.
Diabetic medicine : a journal of the British Diabetic Association.
37(12):2160-2168
[DOI] 10.1111/dme.14361.
[PMID] 32634859.
2020
Introducing the Endotype Concept to Address the Challenge of Disease Heterogeneity in Type 1 Diabetes
Diabetes Care.
43(1):5-12
[DOI] 10.2337/dc19-0880.
[PMID] 31753960.
2020
The risk of progression to type 1 diabetes is highly variable in individuals with multiple autoantibodies following screening
Diabetologia.
63(3):588-596
[DOI] 10.1007/s00125-019-05047-w.
[PMID] 31768570.
2019
Islet amyloidosis in a child with type 1 diabetes
Islets.
11(2):44-49
[DOI] 10.1080/19382014.2019.1599707.
[PMID] 31084520.
2019
Predicting progression to type 1 diabetes from ages 3 to 6 in islet autoantibody positive TEDDY children
Pediatric Diabetes.
20(3):263-270
[DOI] 10.1111/pedi.12812.
[PMID] 30628751.
2019
Who Is Enrolling? The Path to Monitoring in Type 1 Diabetes TrialNet’s Pathway to Prevention
Diabetes Care.
42(12):2228-2236
[DOI] 10.2337/dc19-0593.
[PMID] 31558546.
2018
Immune Mechanisms and Pathways Targeted in Type 1 Diabetes.
Current diabetes reports.
18(10)
[DOI] 10.1007/s11892-018-1066-5.
[PMID] 30168021.
2018
Pancreatic Histopathology of Human Monogenic Diabetes Due to Causal Variants in KCNJ11, HNF1A, GATA6, and LMNA.
The Journal of clinical endocrinology and metabolism.
103(1):35-45
[DOI] 10.1210/jc.2017-01159.
[PMID] 28938416.
2018
Presymptomatic screening for autoimmune β-cell disorder: Baby steps toward prevention?
Pediatric diabetes.
19(1):11-13
[DOI] 10.1111/pedi.12620.
[PMID] 29368416.
2018
Understanding Pre-Type 1 Diabetes: The Key to Prevention.
Frontiers in endocrinology.
9
[DOI] 10.3389/fendo.2018.00070.
[PMID] 29559955.
2017
High Illicit Drug Abuse and Suicide in Organ Donors With Type 1 Diabetes
Diabetes Care.
40(9):e122-e123
[DOI] 10.2337/dc17-0996.
2017
Insulin, insulin antibodies and insulin autoantibodies
.
2017
Insulin, insulin antibodies and insulin autoantibodies.
MLO: medical laboratory observer.
49(2):16-18
[PMID] 30005474.
2017
Poor Adherence to Ketone Testing in Patients With Type 1 Diabetes.
Diabetes care.
40(4):e38-e39
[DOI] 10.2337/dc16-2620.
[PMID] 28100607.
2017
T Cell Receptor Profiling in Type 1 Diabetes.
Current diabetes reports.
17(11)
[DOI] 10.1007/s11892-017-0946-4.
[PMID] 29022222.
2017
Type 1 diabetes mellitus.
Nature reviews. Disease primers.
3
[DOI] 10.1038/nrdp.2017.16.
[PMID] 28358037.
2016
Current and future efforts toward the prevention of type 1 diabetes.
Pediatric diabetes.
17 Suppl 22:78-86
[DOI] 10.1111/pedi.12333.
[PMID] 27411441.
2016
Diagnostic Dilemma: Clinical and Histological Abnormalities in a Hispanic Patient With Diabetes.
Diabetes care.
39(9):1650-2
[DOI] 10.2337/dc16-0711.
[PMID] 27555624.
2016
Presumptive Type 1 Diabetes With Comorbidities and Rapid Progression Despite Numerous Insulin-Positive Islets.
Diabetes care.
39(7):1292-4
[DOI] 10.2337/dc16-0737.
[PMID] 27330131.
2016
Tablet/Capsule Size Variation Among The Most Commonly Prescribed Medications For Children In The Usa: Retrospective Review And Firsthand Pharmacy Audit.
Paediatric drugs.
18(1):65-73
[DOI] 10.1007/s40272-015-0156-y.
[PMID] 26801779.
2015
A Pilot Study Of The Pediatric Oral Medications Screener (Poms).
Hospital pediatrics.
5(11):586-90
[DOI] 10.1542/hpeds.2015-0027.
[PMID] 26526805.
2015
Effectiveness Of Pediatric Pill Swallowing Interventions: A Systematic Review.
Pediatrics.
135(5):883-9
[DOI] 10.1542/peds.2014-2114.
[PMID] 25896843.
2015
Nail Findings In Hand-Foot-And-Mouth Disease.
The Pediatric infectious disease journal.
34(4):449-50
[DOI] 10.1097/INF.0000000000000574.
[PMID] 25764101.
2010
Errors in the diagnosis and management of necrotizing otitis externa.
The Laryngoscope.
120 Suppl 4
[DOI] 10.1002/lary.21673.
[PMID] 21225805.
2010
Errors in the diagnosis and management of necrotizing otitis externa.
Otolaryngology–head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.
143(4):506-9
[DOI] 10.1016/j.otohns.2010.06.924.
[PMID] 20869559.
Grants
Jul 2021
ACTIVE
Development of a Predictive Response Signature to Anti-Thymocyte Globulin in Type 1 Diabetes
Role: Principal Investigator
Funding: NATL INST OF HLTH NIDDK
Feb 2020
ACTIVE
TrialNet Clinical Center infrastructure support services
Role: Co-Investigator
Funding: UNIV OF SOUTH FLORIDA
via NATL INST OF HLTH NIDDK
Nov 2019
– Sep 2021
A Phase 2 Multi-Center, Randomized, Double-Blind, Placebo-Controlled Trial to Evaluate the Safety of TOL-3021 in Patients with New Onset or Established Type 1 Diabetes Mellitus
Role: Principal Investigator
Funding: EMMES
via TOLERION
Aug 2019
ACTIVE
Home Video-Based Telemedicine to Reduce Hypoglycemia Fear in Parents of Young Children (RedCHip)
Role: Co-Investigator
Funding: NEMOURS CHILDRENS CLINIC
via NATL INST OF HLTH NIDDK
Jun 2019
ACTIVE
Diabetes Journey: From systematic screening to intervention
Role: Co-Investigator
Funding: CINCINNATI CHILDRENS HOSPITAL MED CTR
via NATL INST OF HLTH NIDDK
Oct 2018
ACTIVE
T cell receptor sequencing in type 1 diabetes – biomarker discovery and technology development
Role: Co-Investigator
Funding: HELMSLEY CHARITABLE TRUST, LEONA & HARRY
Jun 2018
– Jun 2019
Characterization of T cell Autoreactivity in Type 1 Diabetes
Role: Principal Investigator
Funding: JDRF
Jul 2017
– May 2018
PES Travel Grant
Role: Principal Investigator
Funding: PEDIATRIC ENDOCRINE SOCIETY
via ELI LILLY AND CO
Apr 2016
– Feb 2021
The CD226 amd TIGIT costimulatory Axis in Type 1
Role: Project Manager
Funding: NATL INST OF HLTH NIDDK
Jun 2014
– Apr 2020
TrialNet: University of Florida Clinical Center and Network
Role: Co-Investigator
Funding: NATL INST OF HLTH NIDDK
Education
Fellowship – Pediatric Endocrinology
2015-2018
·
University of Florida
Residency – Pediatrics
2012-2015
·
University of North Carolina
Medical School
2008-2012
·
University of Florida
Contact Details
Phones:
- Business:
- (352) 265-7337
Emails:
- Business:
- lauraj@ufl.edu
Addresses:
- Business Mailing:
-
PO Box 100296
GAINESVILLE FL 32610 - Business Street:
-
1600 SW ARCHER RD
GAINESVILLE FL 32610